Profile of Prescribing Chemotherapy Regimens for High-Risk Acute Leukemia in Children

Cancer is one of the non-communicable diseases but a health problem in world, including Indonesia. The results 2018 Basic Health Research showed that prevalence cancer rose from 1.4% 2013 to 1.8% 2018. Acute Lymphoblastic Leukemia (ALL) malignant disease characterized by progressive infiltration immature lymphoid cells bone marrow and lymphatic organs. , with leukocyte proliferating irregularly uncontrollably. This study aims analyze descriptive profile prescribing high-risk ALL chemotherapy regimens children at hospital East Surabaya. was conducted on inpatients, using National Protocol. protocol consists 4 phases chemotherapy, namely induction, consolidation, intensification maintenance phases. drug administration record data, there were 143 pediatric patients diagnosis ALL. high risk period July August 2022. most widely used classification glucocorticoid group use induction phase 38,17%, 43,2%, 50%. Dexamethasone generic name 38,17% 43,2% for phase. doses based age child, being 1 mg (97,62%) 12 (88,10%).